ABSTRACT

Introduction

General Biological Properties of Glutathione

Concentration of Sulfur-Containing Amino Acids in Vivo

Subcellular Localization of Glutathione in the Brain

Cellular Localization of Glutathione in the Brain

GSH in Neural Cells in Culture

Intercellular Trafficking of Sulfur-Containing Molecules in the CNS

Glutathione

Cysteine/Cystine

Maintenance of Sulfur Balance in the Brain

Role of Astrocytes as Neuroprotectants

Protection against Oxidative Stress

Protection against Glutamate Neurotoxicity

Protection against Potentially Harmful Xenobiotics

Conclusions

References